Growth of necrotic tumors in the presence and absence of inhibitors

DOI10.1016/0025-5564(96)00023-5zbMATH Open0856.92010OpenAlexW4249569159WikidataQ49121734 ScholiaQ49121734MaRDI QIDQ1817442FDOQ1817442

M. A. J. Chaplain, H. M. Byrne

Publication date: 25 February 1997

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(96)00023-5

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zbMATH Keywords

stabilityapoptosisexistencecell lossnecrosisnutrientstime-independent solutionscancer growthproliferating cellsgrowth of multicellular spheroidsinhibitor-free settinginhibitor-present settingnecrotic cells

Mathematics Subject Classification ID

Medical applications (general) (92C50) Probabilistic models, generic numerical methods in probability and statistics (65C20) Reaction-diffusion equations (35K57) Free boundary problems for PDEs (35R35) Applications to the sciences (65Z05)

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Cited In (only showing first 100 items - show all)

• Stability and instability of Liapunov-Schmidt and Hopf bifurcation for a free boundary problem arising in a tumor model
• The role of growth factors in avascular tumour growth
• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• Stability of solutions to a mathematical model for necrotic tumor growth with time delays in proliferation
• Qualitative analysis of a delayed free boundary problem for tumor growth under the effect of inhibitors
• Hopf bifurcation of a mathematical model for growth of tumors with an action of inhibitor and two time delays
• Analysis of a tumor model free boundary problem with action of an inhibitor and nonlinear boundary conditions
• Analysis of a free boundary problem modeling the growth of nonnecrotic tumors with time delays in proliferation
• On the justification of the quasistationary approximation of several parabolic moving boundary problems. Part I
• Initial/boundary-value problems of tumor growth within a host tissue
• Analysis of a free boundary problem for tumor growth in a periodic external environment
• A free boundary problem for a singular system of differential equations: An application to a model of tumor growth
• Global existence for a parabolic-hyperbolic free boundary problem modelling tumor growth
• ON THE EXISTENCE OF SPATIALLY PATTERNED DORMANT MALIGNANCIES IN A MODEL FOR THE GROWTH OF NON-NECROTIC VASCULAR TUMORS
• On the blow-up mechanism of moving boundary problems
• Analysis of a delayed mathematical model for tumor growth
• Analysis of a mathematical model for tumor growth under indirect effect of inhibitors with time delay in proliferation
• Analysis of necrotic core formation in angiogenic tumor growth
• Radially symmetric growth of necrotic tumors and connection with nonnecrotic tumors
• Well-posedness and stability of a multi-dimensional tumor growth model
• Solid tumour growth analysis of necrotic core formation
• A hyperbolic free boundary problem modeling tumor growth: Asymptotic behavior
• In silico modelling of tumour margin diffusion and infiltration: review of current status
• Tumour dynamics and necrosis: Surface tension and stability
• A pharmacologically based multiscale mathematical model of angiogenesis and its use in investigating the efficacy of a new cancer treatment strategy
• Simple ODE models of tumor growth and anti-angiogenic or radiation treatment
• The effect of time delays on the dynamics of avascular tumor growth
• Optimisation of Cancer Drug Treatments Using Cell Population Dynamics
• Bifurcation from stability to instability for a free boundary problem modeling tumor growth by Stokes equation
• Time delays in proliferation process for solid avascular tumour
• Time delays in regulatory apoptosis for solid avascular tumour
• MATHEMATICAL ANALYSIS AND CHALLENGES ARISING FROM MODELS OF TUMOR GROWTH
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• Mathematical model and its fast numerical method for the tumor growth
• Mathematical modelling of tumour growth and treatment
• A mathematical model of the immersion of a spherical tumor with a necrotic core into a nutrient bath
• Multiscale modelling and nonlinear simulation of vascular tumour growth
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• Analysis of a mathematical model of the growth of necrotic tumors
• Modelling the cell cycle and cell movement in multicellular tumour spheroids
• Analysis of a time-delayed mathematical model for solid avascular tumor growth under the action of external inhibitors
• A time-delayed mathematical model for tumor growth with the effect of a periodic therapy
• Modelling the formation of necrotic regions in avascular tumours
• Models of Cell Motion and Tissue Growth
• Analysis of a solid avascular tumor growth model with time delays in proliferation process
• Existence and uniqueness of the global solution for a mathematical model of the use of macrophages in tumor medicine
• Fictitious domains and level sets for moving boundary problems. Applications to the numerical simulation of tumor growth
• The Hele-Shaw asymptotics for mechanical models of tumor growth
• Hopf bifurcation of a free boundary problem modeling tumor growth with two time delays
• Bifurcation for a free boundary problem modeling the growth of multi-layer tumors
• A Free Boundary Problem for an Elliptic–Parabolic System: Application to a Model of Tumor Growth
• Necrotic core in EMT6/Ro tumour spheroids: is it caused by an ATP deficit?
• Continuation along bifurcation branches for a tumor model with a necrotic core
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• Analysis of tumor growth under direct effect of inhibitors with time delays in proliferation
• Analysis of mathematical models for the growth of tumors with time delays in cell proliferation
• Mathematical modeling of gastro-intestinal metastasis resistance to tyrosine kinase inhibitors
• A mathematical model to study the effects of drug resistance and vasculature on the response of solid tumors to chemotherapy
• The impact of time delay and angiogenesis in a tumor model
• Evolving interfaces via gradients of geometry-dependent interior Poisson problems: application to tumor growth
• Asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with fluid-like tissue under the action of inhibitors
• Nonlinear simulation of the effect of microenvironment on tumor growth
• Analysis of a free-boundary tumor model with angiogenesis
• Bifurcation for a free-boundary tumor model with angiogenesis
• A Ritz-Galerkin approximation to the solution of parabolic equation with moving boundaries
• The competitive dynamics between tumor cells, a replication-competent virus and an immune response
• Asymptotic stability for a free boundary problem arising in a tumor model
• Microenvironment driven invasion: a multiscale multimodel investigation
• Symmetry-breaking bifurcation of analytic solutions to free boundary problems: An application to a model of tumor growth
• Modelling the role of cell-cell adhesion in the growth and development of carcinomas
• On interfaces between cell populations with different mobilities
• Bifurcation from stability to instability for a free boundary problem arising in a tumor model
• Analysis of a free boundary problem for avascular tumor growth with a periodic supply of nutrients
• Three-dimensional multispecies nonlinear tumor growth. II: Tumor invasion and angiogenesis
• Three-dimensional multispecies nonlinear tumor growth. I: Model and numerical method
• Qualitative analysis of a free boundary problem for tumor growth under the action of periodic external inhibitors
• Analysis for a free boundary problem modeling tumor therapy
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• A free boundary problem arising from DCIS mathematical model
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• Biparametric identification for a free boundary of ductal carcinoma in situ
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• Intensified doxorubicin-based regimen efficacy in residual non-Hodgkin's lymphoma disease: towards a computationally supported treatment improvement
• Ritz-Galerkin method for solving a parabolic equation with non-local and time-dependent boundary conditions
• Formation and growth of co-culture tumour spheroids: new compartment-based mathematical models and experiments
• Phenotype-structured model of intra-clonal heterogeneity and drug resistance in multiple myeloma
• Another way of solving a free boundary problem related to DCIS model
• Analysis of the growth of a radial tumor with triple-layered structure
• Periodic solution for a free-boundary tumor model with small diffusion-to-growth ratio
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• Analysis of a nonautonomous free boundary tumor model with infinite time delays
• Analysis of a high-dimensional free boundary problem on tumor growth with time-dependent nutrient supply and inhibitor action
• Phenotypic heterogeneity in a model of tumour growth: existence of solutions and incompressible limit
• Asymptotic stability of a free boundary problem for the growth of multi-layer tumours in the necrotic phase

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