A stochastic model for the origin and treatment of tumors containing drug-resistant cells
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Publication:1820076
DOI10.1007/BF02459682zbMath0613.92006WikidataQ52650549 ScholiaQ52650549MaRDI QIDQ1820076
Andrew J. Coldman, James H. Goldie
Publication date: 1986
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
stochastic modelKolmogorov forward equationschemo-sensitive and chemo-resistant cellschemotherapy of experimental tumorsdrug-resistant mutantsjoint probability-generating functionoptimum scheduling of therapy
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Cites Work
- Unnamed Item
- A mathematical model of the effects of drug resistance in cancer chemotherapy
- A model for the resistance of tumor cells to cancer chemotherapeutic agents
- The effect of cellular differentiation on the development of permanent drug resistance
- A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS
