Mathematical analysis of a proposed mechanism for oscillatory insulin secretion in perifused HIT-15 cells

DOI10.1007/BF02460784zbMath0820.92011OpenAlexW1975624100WikidataQ41329034 ScholiaQ41329034MaRDI QIDQ1890525

Laura Weiss Maki, Joel Keizer

Publication date: 18 May 1995

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/bf02460784

zbMATH Keywords

phase plane analysistime-scale analysisGLUT transportersHIT-15kinetics of uptake of glucoseoscillatory secretionrate of glucose metabolismsecretion of insulin

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40) Physiology (general) (92C30) Qualitative theory for ordinary differential equations (34C99)

Related Items (4)

Sustained simultaneous glycolytic and insulin oscillations in \(\beta\)-cells ⋮ Targeted reduction of complex models with time scale hierarchy -- a case study ⋮ Optimizing SGLT inhibitor treatment for diabetes with chronic kidney diseases ⋮ Mathematical models and software tools for the glucose\,-\,insulin regulatory system and diabetes: an overview

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