Analysis of solutions for a cerebrospinal fluid model

DOI10.1016/J.NONRWA.2018.05.009MaRDI QIDQ1994867zbMATH OpenOpenAlexWikidataFDO

Authors Donatella Donatelli, Pierangelo Marcati, Licia Romagnoli

Publication date 2 November 2018

Published in Nonlinear Analysis. Real World Applications (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1705.07744

zbMATH Keywords

cerebrospinal fluid modelhyperbolic systemsiterative processes

Mathematics Subject Classification ID

Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Blow-up in context of PDEs (35B44) Smoothness and regularity of solutions to PDEs (35B65) PDEs in connection with fluid mechanics (35Q35) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite difference methods for initial value and initial-boundary value problems involving PDEs (65M06) Physiological flows (76Z05) Physiological flow (92C35)

Abstract: The main purpose of this manuscript is to analyze an intracranic fluid model from a mathematical point of view. By means of an iterative process we are able to prove the existence and uniqueness of a local solution and the existence and uniqueness of a global solution under some restriction conditions on the initial data. Moreover the last part of the paper is devoted to present numerical simulations for the analyzed cerebrospinal model. In particular, in order to assess the reliability of the stated theoretical results, we carry out the numerical simulations in two different cases: first, we fix initial data which satisfy the conditions for the global existence of solution then, we choose initial data that violate them.

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Cited in

(8)

• A comparison of two mathematical models of the cerebrospinal fluid dynamics
• Nonreflecting boundary conditions for a CSF model of fourth ventricle: spinal SAS dynamics
• On well-posedness of a mathematical model for cerebrospinal fluid in the optic nerve sheath and the spinal subarachnoid space
• The formation of cerebrospinal fluid in the brain (the linearised model)
• Analytic solution during an infusion test of the linear unsteady poroelastic equations in a spherically symmetric model of the brain
• A one-dimensional model for the pulsating flow of cerebrospinal fluid in the spinal canal
• Numerical simulations of different models describing cerebrospinal fluid dynamics
• Three-dimensional cerebrospinal fluid flow within the human central nervous system

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