A mathematical analysis of rebound in a target-mediated drug disposition model. II. With feedback

DOI10.1007/S00285-016-1073-6zbMATH Open1397.92269OpenAlexW4240567946WikidataQ41026450 ScholiaQ41026450MaRDI QIDQ2014347FDOQ2014347

Philip J. Aston, Balaji M. Agoram, Gianne Derks, Piet H. van der Graaf

Publication date: 11 August 2017

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-016-1073-6

zbMATH Keywords

feedbackpharmacodynamicspharmacokineticssystems pharmacologyantibodyreceptor rebound

Mathematics Subject Classification ID

Medical applications (general) (92C50) Inertial manifolds and other invariant attracting sets of infinite-dimensional dissipative dynamical systems (37L25) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Feedback control (93B52)

Cites Work

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• Geometric singular perturbation theory in biological practice
• Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
• Dynamics of target-mediated drug disposition: how a drug reaches its target
• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback

Cited In (1)

• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback

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