Theoretical analysis for a PDE-ODE system related to a glioblastoma tumor with vasculature

DOI10.1007/S00033-021-01530-WzbMATH Open1464.35360arXiv2007.12650OpenAlexW3173726311MaRDI QIDQ2026401FDOQ2026401

Authors: A. Fernández-Romero, Francisco Guillén-González, Antonio Suárez 

Publication date: 19 May 2021

Published in: ZAMP. Zeitschrift für angewandte Mathematik und Physik (Search for Journal in Brave)

Abstract: In this paper we study a PDE-ODE system as a simplification of a Glioblastoma model. Mainly, we prove the existence and uniqueness of global in time classical solution using a fixed point argument. Moreover, we show some stability results of the solution depending on some conditions on the parameters.

Full work available at URL: https://arxiv.org/abs/2007.12650

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zbMATH Keywords

glioblastomaclassical solutionPDE-ODE systemtumor model

Mathematics Subject Classification ID

Stability in context of PDEs (35B35) Asymptotic behavior of solutions to PDEs (35B40) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Nonlinear evolution equations (47J35) Cell biology (92C37) Classical solutions to PDEs (35A09) PDEs of mixed type (35M10)

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Cited In (6)

• Well-posedness of a coupled PDE-ODE model of stem cell lineage involving homeostatic regulation
• Numerical analysis of a mathematical model describing the evolution of hypoxic glioma cells
• Theoretical and numerical analysis of a parabolic system with chemoattraction modeling the growth of glioma cells
• A glioblastoma PDE-ODE model including chemotaxis and vasculature
• Long time behavior of a parabolic \(p\)-Laplacian equation coupled to a compartmental ODE system with an induction threshold phenomenon
• Theoretical and numerical analysis for a hybrid tumor model with diffusion depending on vasculature

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