An inverse problem involving a viscous eikonal equation with applications in electrophysiology

DOI10.1007/S10013-021-00509-4zbMATH Open1479.35953arXiv2006.05481OpenAlexW3169824608MaRDI QIDQ2054698FDOQ2054698

Authors: Philip Trautmann, Karl Kunisch 

Publication date: 3 December 2021

Published in: Vietnam Journal of Mathematics (Search for Journal in Brave)

Abstract: In this work we discuss the reconstruction of cardiac activation instants based on a viscous Eikonal equation from boundary observations. The problem is formulated as an least squares problem and solved by a projected version of the Levenberg Marquardt method. Moreover, we analyze the wellposeness of the state equation and derive the gradient of the least squares functional with respect to the activation instants. In the numerical examples we also conduct an experiment in which the location of the activation sites and the activation instants are reconstructed jointly based on an adapted version of the shape gradient method from https://link.springer.com/article/10.1007/s00285-019-01419-3. We are able to reconstruct the activation instants as well as the locations of the activations with high accuracy relative to the noise level.

Full work available at URL: https://arxiv.org/abs/2006.05481

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zbMATH Keywords

Levenberg-Marquardt method

Mathematics Subject Classification ID

Physiology (general) (92C30) Semilinear elliptic equations (35J61) Boundary value problems for second-order elliptic equations (35J25) Inverse problems for PDEs (35R30)

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Cited In (1)

• Inverse localization of earliest cardiac activation sites from activation maps based on the viscous eikonal equation

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