Existence of a T-periodic solution for the monodomain model corresponding to an isolated ventricle due to ionic-diffusive relations
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Publication:2073597
Medical applications (general) (92C50) Physiology (general) (92C30) Existence problems for PDEs: global existence, local existence, non-existence (35A01) Periodic solutions to PDEs (35B10) Weak solutions to PDEs (35D30) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Biological rhythms and synchronization (92B25)
Abstract: In this paper, we find relations between the ionic parameters and the diffusion parameters which are sufficient to ensure the existence of a periodic solution for a well-known monodomain model in a weak sense. We make use of the method of approximation of Faedo-Galerkin to prove the existence of weak periodic solutions of the monodomain model for the electrical activity of the heart assuming that it is periodically activated in its boundaries. Actually, this periodic solution has the same period of activation. Finally, we reflect on how these ionic-diffusive relations are useful to explain the pathophysiology of some rhythm disorders.
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