A minimal model for synaptic integration in simple neurons

DOI10.1016/J.PHYSD.2021.132988MaRDI QIDQ2077583zbMATH OpenOpenAlexFDO

Authors Adrian Alva, Harjinder Singh

Publication date 21 February 2022

Published in Physica D (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/2012.05454

zbMATH Keywords

stochastic resonancecoherence resonanceneuronssynaptic integration

Mathematics Subject Classification ID

Neural biology (92C20)

Abstract: Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of excitatory inputs from synapses and illustrate its use by characterizing some functional properties of postsynaptic neurons. In this regard, we study the response of postsynaptic neurons as defined by the model to two well known noise driven processes: stochastic and coherence resonance. The model requires a small number of parameters and is especially useful to isolate the role of integration mechanisms that rely on summation of inputs with little dendritic processing.

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Cited in

(9)

• Analysis of the dendritic integration of excitatory and inhibitory inputs using cable models
• Neural information processing and computations of two-input synapses
• Linearization of excitatory synaptic integration at no extra cost
• Effects of Synaptic Synchrony on the Neuronal Input-Output Relationship
• Predicting the synaptic information efficacy in cortical layer 5 pyramidal neurons using a minimal integrate-and-fire model
• A mathematical model of information transfer in ribbon synapses
• Simplicity and Efficiency of Integrate-and-Fire Neuron Models
• A review of the integrate-and-fire neuron model: I. Homogeneous synaptic input
• Activity-driven computational strategies of a dynamically regulated integrate-and-fire model neuron

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