Computational tools for assessing gene therapy under branching process models of mutation
DOI10.1007/S11538-021-00969-2zbMath1484.92047arXiv2111.08183OpenAlexW3212400960WikidataQ113900100 ScholiaQ113900100MaRDI QIDQ2079001
Janet S. Sinsheimer, Mary Sehl, Jason Xu, Timothy C. Stutz
Publication date: 4 March 2022
Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)
Full work available at URL: https://arxiv.org/abs/2111.08183
generating functionsconditional momentshematopoiesismechanistic modelsmutagenesisstochastic population processes
Applications of branching processes (60J85) Medical applications (general) (92C50) Genetics and epigenetics (92D10) Computational methods for problems pertaining to biology (92-08)
Uses Software
Cites Work
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- Transition probabilities for general birth-death processes with applications in ecology, genetics, and evolution
- An exact representation for the generating function for the Moolgavkar-Venzon-Knudson two-stage model of carcinogenesis with stochastic stem cell growth
- Genetic instability and clonal expansion
- Stochastic dynamics of metastasis formation
- Statistical inference for partially observed branching processes with application to cell lineage tracking of \textit{in vivo} hematopoiesis
- Likelihood-based inference for discretely observed birth-death-shift processes, with applications to evolution of mobile genetic elements
- Julia: A Fresh Approach to Numerical Computing
- Applied Probability
- Calculation of the Equilibrium Distribution for a Deleterious Gene by the Finite Fourier Transform
- Branching Process Models of Cancer
- Branching Processes Since 1873
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