A multi-drug pharmacokinectic optimal control approach in cancer chemotherapy

DOI10.1007/S10957-022-02085-0MaRDI QIDQ2082249zbMATH OpenOpenAlexFDO

Authors M. P. Rajan, C. K. Nanditha

Publication date 4 October 2022

Published in Journal of Optimization Theory and Applications (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s10957-022-02085-0

zbMATH Keywords

cancerchemotherapymathematical modelingoptimal control

Mathematics Subject Classification ID

Existence theories for optimal control problems involving ordinary differential equations (49J15) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

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Cites work

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• scientific article; zbMATH DE number 3490676 (Why is no real title available?)
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• Immunotherapy: an optimal control theory approach
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• Optimal bang-bang controls for a two-compartment model in cancer chemotherapy
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Cited in

(9)

• Reinforcement learning-based control of drug dosing for cancer chemotherapy treatment
• Mixed therapy in cancer treatment for personalized drug administration using model reference adaptive control
• Optimized drug regimen and chemotherapy scheduling for cancer treatment using swarm intelligence
• An integrated multiscale mechanistic model for cancer drug therapy
• The impact of competition between cancer cells and healthy cells on optimal drug delivery
• Optimal control for a mathematical model for chemotherapy with pharmacometrics
• An adaptive pharmacokinetic optimal control approach in chemotherapy for heterogeneous tumor
• A robust optimal control framework for controlling aberrant RTK signaling pathways in esophageal cancer
• A model-based optimal distributed predictive management of multidrug infusion in lung cancer patient therapy

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