Mathematical models of leukaemia and its treatment: a review

DOI10.1007/S40324-022-00296-ZMaRDI QIDQ2089013zbMATH OpenOpenAlexFDO

Authors Yanyan Li

Publication date 6 October 2022

Published in S\(\vec{\text{e}}\)MA Journal (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://arxiv.org/abs/2011.05881

zbMATH Keywords

differential equations mathematical model treatment leukaemia

Mathematics Subject Classification ID

Medical applications (general) (92C50) Dynamical systems in biology (37N25) Mathematical modeling or simulation for problems pertaining to biology (92-10) PDEs in connection with biology, chemistry and other natural sciences (35Q92)

Abstract: Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the use of mathematical models in oncology to draw inferences and make predictions, providing a complementary picture to experimental biomedical models. In this paper we recapitulate the state of the art of mathematical modelling of leukaemia growth dynamics, in time and response to treatment. We intend to describe the mathematical methodologies, the biological aspects taken into account in the modelling, and the conclusions of each study. This review is intended to provide researchers in the field with solid background material, in order to achieve further breakthroughs in the promising field of mathematical biology.

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