A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate response

DOI10.1016/J.JTBI.2022.111293OpenAlexW4302009284MaRDI QIDQ2095409FDOQ2095409

Authors: Andreas C. Aristotelous, M. Gregory Forest, Alex W. J. Chen 

Publication date: 9 November 2022

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2022.111293

zbMATH Keywords

COVID-19simulationscellular automatoninnate immunitypneumonia

Mathematics Subject Classification ID

Biology and other natural sciences (92-XX)

Cites Work

• Direct Methods for Sparse Linear Systems
• Title not available (Why is that?)
• A novel time integration method for solving a large system of non-linear algebraic equations
• Title not available (Why is that?)
• Chemical evolutionary games
• Fingering in Stochastic Growth Models

Cited In (2)

• A low dimensional dynamical model of the initial pulmonary innate response to infection
• Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection

Uses Software

• CSparse

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