Identifying optimal adaptive therapeutic schedules for prostate cancer through combining mathematical modeling and dynamic optimization

DOI10.1016/J.APM.2022.03.004MaRDI QIDQ2109575zbMATH OpenOpenAlexFDO

Authors Ruiyang Liu, Shun Wang, Xuewen Tan, Xiufen Zou

Publication date 21 December 2022

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2022.03.004

zbMATH Keywords

adaptive therapydynamic optimizationmathematical modeloptimal therapeutic scheduleprostate cancer

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Deterministic scheduling theory in operations research (90B35) Medical applications (general) (92C50)

Cites work

• Global asymptotic stability in a periodic Lotka-Volterra system

Cited in

(8)

• Comment
• Dynamic analysis of a drug resistance evolution model with nonlinear immune response
• Effects of diffusion on dynamics of a competition system between drug-sensitive and drug-resistant cancer cells
• Mathematical modelling of tumor-immune interactions in breast cancer
• Optimal adaptive therapeutic schedules for metastatic castrate-resistant prostate cancer based on bilevel optimization problem
• Analysis and optimization control of lung cancer treatment based on surgical resection and immune cell therapy
• Combined hormone and brachy therapies for the treatment of prostate cancer
• A tumor model of drug resistance with mixed immunotherapy and chemotherapy: parameter estimation and dynamical analysis

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