Effects of cell permeability on distribution and penetration of drug into biological tissues: a multiscale approach

DOI10.1016/J.APM.2022.03.037MaRDI QIDQ2109612zbMATH OpenOpenAlexWikidataFDO

Authors Kalp Nath Singh Yadav, D. C. Dalal

Publication date 21 December 2022

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2022.03.037

zbMATH Keywords

biological tissuedrug deliverymultiscalepartition phenomenonpassive diffusionpermeable membrane

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell biology (92C37)

Cites work

• A multiscale analysis of nutrient transport and biological tissue growth in vitro
• A numerical method for mass transfer by a thin moving membrane with selective permeabilities
• An immersed boundary method for mass transfer across permeable moving interfaces
• An immersed boundary method for mass transfer through porous biomembranes under large deformations
• An immersed boundary method for restricted diffusion with permeable interfaces
• Analysis of the heterogeneous multiscale method for parabolic homogenization problems
• Multi-scale analysis for concentration distribution in an oscillatory Couette flow
• Multiscale finite-volume method for parabolic problems arising from compressible multiphase flow in porous media
• Multiscale homogenization for fluid and drug transport in vascularized malignant tissues
• Multiscale modelling of fluid and drug transport in vascular tumours
• Parallel iterative methods for sparse linear systems
• Solving immersed interface problems using a new interfacial points-based finite difference approach
• The effect of interstitial pressure on tumor growth: coupling with the blood and lymphatic vascular systems
• The heterogeneous multiscale method to study particle size and partitioning effects in drug delivery
• The heterogeneous multiscale methods
• The role of the microvascular tortuosity in tumor transport phenomena

Cited in

(4)

• A phase field model for mass transport with semi-permeable interfaces
• A multiscale computational study of the effects of fluid flow and drug metabolism on drug delivery
• Penetration and distribution efficacy of chemotherapeutic drugs in biological tissues: a computational investigation
• Effects of cell orientation on drug delivery into biological tissues: a computational study

Describes a project that uses

Uses Software

• Matlab

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