A minimal model of glucose-stimulated insulin secretion process explores factors responsible for the development of type 2 diabetes

DOI10.1016/J.APM.2022.03.035MaRDI QIDQ2109620zbMATH OpenOpenAlexFDO

Authors Abhijit Paul, Phonindra Nath Das, S. Chatterjee

Publication date 21 December 2022

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2022.03.035

zbMATH Keywords

glucose-stimulated insulin secretioninsulininsulin resistanceparameter recalibrationsensitivity analysistype 2 diabetes

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Cell biology (92C37) Biochemistry, molecular biology (92C40)

Cites work

• Bursting, chaos and birhythmicity originating from self-modulation of the inositol 1,4,5-trisphosphate signal in a model for intracellular Ca\(^{2+}\) oscillations
• Comparison of the tangent model predictions to finite element results for the solution of the inclusion problem in viscoplasticity
• Delay in ATP-dependent calcium inflow may affect insulin secretion from pancreatic beta-cell
• scientific article; zbMATH DE number 3100403 (Why is no real title available?)
• Mathematical modeling of the glucose-insulin system: a review
• Mathematical modelling of hepatic lipid metabolism
• Mathematical modelling of the intravenous glucose tolerance test
• Mathematical models and software tools for the glucose\,-\,insulin regulatory system and diabetes: an overview
• Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: An HIV Model, as an Example

Cited in

(5)

• Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression
• A minimal mathematical model to study insulin synthesis and secretion process
• The application of a model of glucose and insulin dynamics to explain an observed effect of leptin administration in reversal of developmental programming
• Interactive dynamics of \(\mathrm{Ca}^{2+}\) and ATP regulating ADP and insulin secretion in a \(\beta\)-cell
• Insulin resistance or hypersecretion? the \(\beta\)IG picture revisited

This page was built for publication: A minimal model of glucose-stimulated insulin secretion process explores factors responsible for the development of type 2 diabetes

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2109620)