Oscillations and bifurcation structure of reaction-diffusion model for cell polarity formation

DOI10.1007/S00285-022-01723-5zbMATH Open1485.35045arXiv2104.04283OpenAlexW3152680424WikidataQ113905399 ScholiaQ113905399MaRDI QIDQ2113522FDOQ2113522

Shin-Ichiro Ei, Hirofumi Izuhara, Masataka Kuwamura

Publication date: 14 March 2022

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Abstract: We investigate the oscillatory dynamics and bifurcation structure of a reaction-diffusion system with bistable nonlinearity and mass conservation, which was proposed by [Otsuji et al, PLoS Comp. Biol. 3 (2007), e108]. The system is a useful model for understanding cell polarity formation. We show that this model exhibits four different spatiotemporal patterns including two types of oscillatory patterns, which can be regarded as cell polarity oscillations with the reversal and non-reversal of polarity, respectively. The trigger causing these patterns is a diffusion-driven (Turing-like) instability. Moreover, we investigate the effects of extracellular signals on the cell polarity oscillations.

Full work available at URL: https://arxiv.org/abs/2104.04283

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zbMATH Keywords

reaction-diffusion systembistable nonlinearitycell polarity oscillations

Mathematics Subject Classification ID

Bifurcations in context of PDEs (35B32) Pattern formations in context of PDEs (35B36) Initial-boundary value problems for second-order parabolic systems (35K51) Reaction-diffusion equations (35K57) General biology and biomathematics (92B05)

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Cited In (4)

• Single transition layer in mass-conserving reaction-diffusion systems with bistable nonlinearity
• Stability of cellular wave structures in oscillatory pattern-forming systems near onset
• Oscillation and pattern formation in a system of self-regulating cells
• A PDE-DDE model for cell polarization in fission yeast

Uses Software

• AUTO
• AUTO-07P

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