Identifiable paths and cycles in linear compartmental models
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Publication:2127647
Abstract: We introduce a class of linear compartmental models called identifiable path/cycle models which have the property that all of the monomial functions of parameters associated to the directed cycles and paths from input compartments to output compartments are identifiable and give sufficient conditions to obtain one. Removing leaks, we then show how one can obtain a locally identifiable model from an identifiable path/cycle model. These identifiable path/cycle models yield the only identifiable models with certain conditions on their graph structure and thus we provide necessary and sufficient conditions for identifiable models with certain graph properties. A sufficient condition based on the graph structure of the model is also provided so that one can test if a model is an identifiable path/cycle model by examining the graph itself. We also provide some necessary conditions for identifiability based on graph structure. Our proofs use algebraic and combinatorial techniques.
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Cites work
- Algebraic Graph Theory
- Algebraic tools for the analysis of state space models
- Compartmental-model response function for dendritic trees
- Global approaches to identifiability testing for linear and nonlinear state space models
- Global identifiability of differential models
- scientific article; zbMATH DE number 4200085 (Why is no real title available?)
- scientific article; zbMATH DE number 44386 (Why is no real title available?)
- scientific article; zbMATH DE number 52497 (Why is no real title available?)
- Identifiability of linear compartmental models: the effect of moving inputs, outputs, and leaks
- Identifiability results for several classes of linear compartment models
- Identifiable reparametrizations of linear compartment models
- Linear compartmental models: input-output equations and operations that preserve identifiability
- Observability and structural identifiability of nonlinear biological systems
- On global identifiability for arbitrary model parametrizations
- On the existence of identifiable reparametrizations for linear compartment models
- Parameter identifiability of nonlinear systems: The role of initial conditions.
- Similarity transformation approach to identifiability analysis of nonlinear compartmental models
- System identifiability based on the power series expansion of the solution
Cited in
(13)- Analysis of unique structural identifiability via submodels
- On some topological properties of a strongly connected compartmental system with application to the identifiability problem
- Identifiable reparametrizations of linear compartment models
- Identifiability of linear compartmental tree models and a general formula for input-output equations
- scientific article; zbMATH DE number 444251 (Why is no real title available?)
- On the existence of identifiable reparametrizations for linear compartment models
- Identifiability of linear compartmental models: the effect of moving inputs, outputs, and leaks
- Linear compartmental models: input-output equations and operations that preserve identifiability
- A kinetic finite volume discretization of the multidimensional PIDE model for gene regulatory networks
- Graph-based sufficient conditions for the indistinguishability of linear compartmental models
- Identifiability of directed-cycle and catenary linear compartmental models
- Parameter identifiability of linear-compartmental mammillary models
- Identifiability results for several classes of linear compartment models
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