Mathematical modelling highlights the potential for genetic manipulation as an adjuvant to counter efflux-mediated MDR in \textit{Salmonella}

DOI10.1007/S11538-022-01011-9MaRDI QIDQ2127657zbMATHOpenAlexWikidataFDO

Authors George Youlden, Helen E. McNeil, Jessica M. A. Blair, Sara Jabbari, J. R. King

Publication date 21 April 2022

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-022-01011-9

zbMATH Keywords

mathematical modellingparameter fitting\textit{Salmonella}efflux pumpsresistance-nodulation-division

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Microbiology (92C70)

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Cites work

• scientific article; zbMATH DE number 5180707 (Why is no real title available?)
• A Comparison of Three Methods for Selecting Values of Input Variables in the Analysis of Output from a Computer Code
• A mathematical model for the inhibition of the multidrug resistance- associated \(p\)-glycoprotein pump
• A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
• Convergence Properties of the Nelder--Mead Simplex Method in Low Dimensions
• Time dependent asymptotic analysis of the gene regulatory network of the AcrAB-TolC efflux pump system in gram-negative bacteria

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Uses Software

• fminsearch

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