Altered neuronal excitability in a Hodgkin-Huxley model incorporating channelopathies of the delayed rectifier Potassium channel

DOI10.1007/S10827-020-00766-1zbMATH Open1489.92038OpenAlexW3093197233WikidataQ100664173 ScholiaQ100664173MaRDI QIDQ2137286FDOQ2137286

Allan Gottschalk, Omar A. Hafez

Publication date: 16 May 2022

Published in: Journal of Computational Neuroscience (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s10827-020-00766-1

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zbMATH Keywords

Hopf bifurcationnonlinear dynamical systemHodgkin-Huxley modelneuronal excitabilityepisodic ataxia type 1Kv1.1 channelopathy

Mathematics Subject Classification ID

Neural biology (92C20) Pathology, pathophysiology (92C32)

Cites Work

• Nonlinear oscillations, dynamical systems, and bifurcations of vector fields
• Local birth of homoclinic chaos
• NEURAL EXCITABILITY, SPIKING AND BURSTING
• Numerical calculation of stable and unstable periodic solutions to the Hodgkin-Huxley equations
• New features of the software M<scp>at</scp>C<scp>ont</scp>for bifurcation analysis of dynamical systems
• Chaos in the Hodgkin--Huxley Model
• The entwined wiggling of homoclinic curves emerging from saddle-node/Hopf instabilities
• Title not available (Why is that?)
• Bifurcation of the Hodgkin and Huxley equations: A new twist
• Hopf bifurcations in multiple-parameter space of the Hodgkin-Huxley equations. I: Global organization of bistable periodic solutions
• Computing Hopf Bifurcations. II: Three Examples From Neurophysiology
• Two-parameters Hopf bifurcation in the Hodgkin-Huxley model

Cited In (2)

• Slowly-inactivating potassium conductances in compartmental interneuron models
• The potassium A-current, low firing rates and rebound excitation in Hodgkin-Huxley models

Uses Software

• MATCONT

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