Web-based structural identifiability analyzer

DOI10.1007/978-3-030-85633-5_17MaRDI QIDQ2142124zbMATH OpenOpenAlexFDO

Authors Ilia Ilmer, Alexey Ovchinnikov, Gleb Pogudin

Publication date 25 May 2022

Full work available at URL https://arxiv.org/abs/2106.15066

zbMATH Keywords

differential algebrastructural identifiabilityidentifiability software

Mathematics Subject Classification ID

Systems biology, networks (92C42) Software, source code, etc. for problems pertaining to biology (92-04)

Abstract: Parameter identifiability describes whether, for a given differential model, one can determine parameter values from model equations. Knowing global or local identifiability properties allows construction of better practical experiments to identify parameters from experimental data. In this work, we present a web-based software tool that allows to answer specific identifiability queries. Concretely, our toolbox can determine identifiability of individual parameters of the model and also provide all functions of parameters that are identifiable (also called identifiable combinations) from single or multiple experiments. The program is freely available at https://maple.cloud/app/6509768948056064.

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Cites work

• A new version of DAISY to test structural identifiability of biological models
• Computing all identifiable functions of parameters for ODE models
• Global identifiability of differential models
• Observability and structural identifiability of nonlinear biological systems
• On identifiability of nonlinear ODE models and applications in viral dynamics
• Parameter estimation of some epidemic models. The case of recurrent epidemics caused by respiratory syncytial virus
• Parameter identifiability of nonlinear systems: The role of initial conditions.

Cited in

(5)

• Differential Elimination for Dynamical Models via Projections with Applications to Structural Identifiability
• Computing parameter identifiability and other structural properties for natural resource models
• A new version of DAISY to test structural identifiability of biological models
• Global identifiability of differential models
• SIAN

Describes a project that uses

Uses Software

• DAISY
• GenSSI
• COMBOS
• SIAN

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