Relation between the number of peaks and the number of reciprocal sign epistatic interactions

DOI10.1007/S11538-022-01029-ZzbMATH Open1497.92180OpenAlexW4283013788WikidataQ113900041 ScholiaQ113900041MaRDI QIDQ2155689FDOQ2155689

Authors: Raimundo Saona, Fyodor A. Kondrashov, Ksenia A. Khudiakova 

Publication date: 15 July 2022

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-022-01029-z

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zbMATH Keywords

Morse theorymultiple peaksfitness landscapesreciprocal sign epistasis

Mathematics Subject Classification ID

Problems related to evolution (92D15)

Cites Work

• Morse theory for cell complexes
• Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes
• The peaks and geometry of fitness landscapes
• An evolution-based model for designing chorismate mutase enzymes

Cited In (3)

• Occurrences of reciprocal sign epistasis in single- and multi-peaked theoretical fitness landscapes
• Evolutionary accessibility of random and structured fitness landscapes
• Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes

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