Mathematical modeling of the receptor-mediated endocytosis process of targeted therapeutic agents in drug delivery systems

DOI10.1016/J.APM.2019.10.037MaRDI QIDQ2174348zbMATH OpenOpenAlexFDO

Authors Jong Hyuk Byun, Il Hyo Jung

Publication date 21 April 2020

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.apm.2019.10.037

zbMATH Keywords

stochastic differential equationsnanoparticlesreceptor-mediated endocytosisage-structured model for payload releaseantibody drug conjugatesstochastic quasi steady state approximation model

Mathematics Subject Classification ID

Applications of continuous-time Markov processes on discrete state spaces (60J28) Biochemistry, molecular biology (92C40) Stochastic ordinary differential equations (aspects of stochastic analysis) (60H10)

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Cites work

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• Mathematical modeling of antibody drug conjugates with the target and tubulin dynamics to predict AUC
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• Modeling in biopharmaceutics, pharmacokinetics, and pharmacodynamics. Homogeneous and heterogeneous approaches.
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• The Monte Carlo Method

Cited in

(4)

• A mathematical model for NIR light protocol optimization in controlled transdermal drug delivery
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• Phase-specific cancer-immune model considering acquired resistance to therapeutic agents
• Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes

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• SDE Toolbox

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