Linking demyelination to compound action potential dispersion with a spike-diffuse-spike approach

DOI10.1186/S13408-019-0071-6MaRDI QIDQ2179525zbMATH OpenOpenAlexWikidataFDO

Authors Richard Naud, A. Longtin

Publication date 12 May 2020

Published in The Journal of Mathematical Neuroscience (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1186/s13408-019-0071-6

zbMATH Keywords

axonal propagationdemyelinating diseasesspike timing variability

Mathematics Subject Classification ID

Neural biology (92C20)

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Cites work

• A Markov chain model of extrabinomial variation
• An edge dislocation interacting with a wedge-shaped bi-material interface
• Conduction in bundles of demyelinated nerve fibers: computer simulation
• Electrical interactions via the extracellular potential near cell bodies
• Ephaptic coupling of myelinated nerve fibers
• Intrinsic dendritic filtering gives low-pass power spectra of local field potentials
• Introduction to Theoretical Neurobiology
• Predicting spike timing of neocortical pyramidal neurons by simple threshold models
• Stimulation-induced ectopicity and propagation windows in model damaged axons
• Stochastic processes in physics and chemistry.
• Why spikes? Hebbian learning and retrieval of time-resolved excitation patterns

Cited in

(5)

• Primary paranode demyelination modulates slowly developing axonal depolarization in a model of axonal injury
• Compromised axonal functionality after neurodegeneration, concussion and/or traumatic brain injury
• Effects of focal axonal swelling level on the action potential signal transmission
• Multiple sclerosis plaques on nervous pathways: a computational model using neural networks
• Propagation failure along myelinated nerves

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