Bayesian factor models for probabilistic cause of death assessment with verbal autopsies

DOI10.1214/19-AOAS1253zbMATH Open1439.62220arXiv1803.01327WikidataQ125290601 ScholiaQ125290601MaRDI QIDQ2179963FDOQ2179963

Authors: T. Kunihama, Zehang Richard Li, Samuel J. Clark, Tyler H. Mccormick 

Publication date: 13 May 2020

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Abstract: The distribution of deaths by cause provides crucial information for public health planning, response, and evaluation. About 60% of deaths globally are not registered or given a cause, limiting our ability to understand disease epidemiology. Verbal autopsy (VA) surveys are increasingly used in such settings to collect information on the signs, symptoms, and medical history of people who have recently died. This article develops a novel Bayesian method for estimation of population distributions of deaths by cause using verbal autopsy data. The proposed approach is based on a multivariate probit model where associations among items in questionnaires are flexibly induced by latent factors. Using the Population Health Metrics Research Consortium labeled data that include both VA and medically certified causes of death, we assess performance of the proposed method. Further, we estimate important questionnaire items that are highly associated with causes of death. This framework provides insights that will simplify future data collection.

Full work available at URL: https://arxiv.org/abs/1803.01327

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zbMATH Keywords

conditional dependencemultivariate datasurvey datacause of deathBayesian latent modelverbal autopsies

Mathematics Subject Classification ID

Factor analysis and principal components; correspondence analysis (62H25) Reliability and life testing (62N05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical epidemiology (92C60) Epidemiology (92D30)

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Cited In (4)

• A flexible Bayesian framework to estimate age- and cause-specific child mortality over time from sample registration data
• Using Bayesian latent Gaussian graphical models to infer symptom associations in verbal autopsies
• Verbal autopsy methods with multiple causes of death
• Bayesian factor models for probabilistic cause of death assessment with verbal autopsies

Uses Software

• R
• Ox
• BayesDA

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