A proposal for using the ensemble approach to understand genetic regulatory networks

DOI10.1016/j.jtbi.2003.12.017zbMath1447.92168OpenAlexW2058942402WikidataQ40483450 ScholiaQ40483450MaRDI QIDQ2186529

Stuart A. Kauffman

Publication date: 9 June 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2003.12.017

zbMATH Keywords

systems biologygenetic regulatory networksensemble approachstatistical observables

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10) Systems biology, networks (92C42)

Related Items (8)

Intrinsic properties of Boolean dynamics in complex networks ⋮ A model of sequential branching in hierarchical cell fate determination ⋮ Stochastic and delayed stochastic models of gene expression and regulation ⋮ Perturbation avalanches and criticality in gene regulatory networks ⋮ Studying genetic regulatory networks at the molecular level: delayed reaction stochastic models ⋮ Boolean dynamics of Kauffman models with a scale-free network ⋮ Reduction of a stochastic model of gene expression: Lagrangian dynamics gives access to basins of attraction as cell types and metastabilty ⋮ Molecular systems biology and control

Cites Work

• Effects of alternative connectivity on behavior of randomly constructed Boolean networks
• Closing probabilities in the Kauffman model: An annealed computation
• Genetic network models and statistical properties of gene expression data in knock-out experiments
• An order parameter for networks of automata

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