An algebra of dimerization and its implications for G-protein coupled receptor signaling

DOI10.1016/J.JTBI.2004.03.012MaRDI QIDQ2189267zbMATH OpenOpenAlexWikidataFDO

Authors Peter J. Woolf, Jennifer J. Linderman

Publication date 15 June 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2004.03.012

zbMATH Keywords

self-organizationMonte Carlo simulationsignal transductiondimerizationdopaminedrug designinternalizationprotein-protein interactionsG-protein coupled receptordimerization algebradimerization networksFRETsomatastatin

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

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Cited in

(5)

• Allostery in oligomeric receptor models
• Modeling and genetic algorithm optimization of early events in signal transduction via dynamics of G-protein-coupled receptors: Internalization consideration
• Ligand binding dynamics for pre-dimerised G protein-coupled receptor homodimers: linear models and analytical solutions
• Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: can a single model explain disparate results?
• Modeling and optimization of G-protein coupled receptor signal transduction

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