An algebra of dimerization and its implications for G-protein coupled receptor signaling

DOI10.1016/J.JTBI.2004.03.012zbMATH Open1440.92034OpenAlexW2095202899WikidataQ44944723 ScholiaQ44944723MaRDI QIDQ2189267FDOQ2189267

Authors: Peter J. Woolf, Jennifer J. Linderman 

Publication date: 15 June 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2004.03.012

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zbMATH Keywords

self-organizationMonte Carlo simulationsignal transductiondimerizationdopaminedrug designinternalizationprotein-protein interactionsG-protein coupled receptordimerization algebradimerization networksFRETsomatastatin

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Cited In (5)

• Allostery in oligomeric receptor models
• Modeling and genetic algorithm optimization of early events in signal transduction via dynamics of G-protein-coupled receptors: Internalization consideration
• Ligand binding dynamics for pre-dimerised G protein-coupled receptor homodimers: linear models and analytical solutions
• Collision coupling, crosstalk, and compartmentalization in G-protein coupled receptor systems: can a single model explain disparate results?
• Modeling and optimization of G-protein coupled receptor signal transduction

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