Small binding-site clearance delays are not negligible in gene expression modeling

DOI10.1016/J.MBS.2020.108376MaRDI QIDQ2197751zbMATH OpenOpenAlexWikidataFDO

Authors Elizabeth A. M. Trofimenkoff, Marc R. Roussel

Publication date 1 September 2020

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2020.108376

zbMATH Keywords

delaysbinding-site clearancegene expression modelingprocessive enzymes

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Qualitative investigation and simulation of models involving functional-differential equations (34K60) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• A delayed mass-action model for the transcriptional control of Hmp, an NO detoxifying enzyme, by the iron-sulfur protein FNR
• Genetic control models with diffusion and delays
• Reduction and stability analysis of a transcription-translation model of RNA polymerase
• SOME HARMLESS DELAYS
• Stochastic kinetics description of a simple transcription model
• Totally asymmetric exclusion processes with particles of arbitrary size

Cited in

(2)

• Graph-based, dynamics-preserving reduction of (bio)chemical systems
• Long lived transients in gene regulation

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