Nonlinear modelling approach to human promoter sequences

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Publication:2199263

DOI10.1016/J.JTBI.2006.01.015zbMATH Open1447.92267arXivq-bio/0505015OpenAlexW2097835715WikidataQ51948383 ScholiaQ51948383MaRDI QIDQ2199263FDOQ2199263

Huijie Yang, Jian-Zhong Gu, Fangcui Zhao, Bing-Hong Wang

Publication date: 16 September 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Abstract: By means of the nonlinear modeling technique (NM technique), we find the nonlinear deterministic structures in the promoter regions (PPRs) of DNA sequences, called deterministic valleys (DVs) in this paper. These DVs prefer to occur much more outside of a special region around TSS. The number, positions and shapes of the DVs are basically different for different PPRs. Generally, these DVs do not occur in the CpG islands, which tells us that they should be special structures with new biological functions rather than the CpG islands. PACS numbers: 87.14.Gg, 87.10.1e, 05.45.2a


Full work available at URL: https://arxiv.org/abs/q-bio/0505015




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