An integrated model of thermodynamic-hemodynamic-pharmacokinetic system and its application on decoupling control of intracranial temperature and pressure in brain hypothermia treatment

DOI10.1016/J.JTBI.2006.01.033MaRDI QIDQ2201823zbMATH OpenOpenAlexWikidataFDO

Authors Lu Gaohua, Tsuyoshi Maekawa, Hidenori Kimura

Publication date 17 September 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2006.01.033

zbMATH Keywords

modelcontroltemperatureintracranial pressure (ICP)brain hypothermia treatment (BHT)

Mathematics Subject Classification ID

Medical applications (general) (92C50) Neural biology (92C20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Pathology, pathophysiology (92C32)

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Cites work

• A mathematical model of intracranial pressure dynamics for brain hypothermia treatment
• A whole-body mathematical model for intracranial pressure dynamics

Cited in

(4)

• Targeted brain hypothermia induced by an interstitial cooling device in the rat neck: Experimental study and model validation
• Modeling selective therapeutic hypothermia in case of acute ischemic stroke using a 1D hemodynamics model and a simplified brain geometry
• A mathematical model of intracranial pressure dynamics for brain hypothermia treatment
• Brain cooling maintenance with cooling cap following induction with intracarotid cold saline infusion: a quantitative model

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