The ratio of P40 monomer to dimer is an important determinant of IL-12 bioactivity

DOI10.1016/J.JTBI.2005.09.022MaRDI QIDQ2202129zbMATH OpenOpenAlexWikidataFDO

Authors David J. Klinke

Publication date 17 September 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2005.09.022

zbMATH Keywords

humanmathematical modeldendritic cellscytokinescytokine receptors

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

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Cited in

(2)

• Monotonicity of interleukin-1 receptor-ligand binding with respect to antagonist in the presence of decoy receptor
• Quantitative assessment of extracellular IL-1 regulation

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