The ratio of P40 monomer to dimer is an important determinant of IL-12 bioactivity

DOI10.1016/J.JTBI.2005.09.022zbMATH Open1447.92138OpenAlexW2043969895WikidataQ44916973 ScholiaQ44916973MaRDI QIDQ2202129FDOQ2202129

Authors: David J. Klinke 

Publication date: 17 September 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2005.09.022

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zbMATH Keywords

humanmathematical modeldendritic cellscytokinescytokine receptors

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Cited In (2)

• Quantitative assessment of extracellular IL-1 regulation
• Monotonicity of interleukin-1 receptor-ligand binding with respect to antagonist in the presence of decoy receptor

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