Signal analysis of impulse response functions in MR and CT measurements of cerebral blood flow

DOI10.1016/J.JTBI.2005.10.005MaRDI QIDQ2202149zbMATH OpenOpenAlexWikidataFDO

Authors Evelyn Rost, Ralf Geske, Michael Baake

Publication date 17 September 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/q-bio/0507042

zbMATH Keywords

Fourier transformblood flowMR and CT imagingparametric fitstissue determination

Mathematics Subject Classification ID

Biomedical imaging and signal processing (92C55) Physiological flow (92C35)

Abstract: The impulse response function (IRF) of a localized bolus in cerebral blood flow codes important information on the tissue type. It is indirectly accessible both from MR- and CT-imaging methods, at least in principle. In practice, however, noise and limited signal resolution render standard deconvolution techniques almost useless. Parametric signal descriptions look more promising, and it is the aim of this contribution to develop some improvements along this line.

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(5)

• Transfer function analysis of respiratory and cardiac pulsations in human brain observed on dynamic magnetic resonance images
• Complete monotonicity of flow and cross-sectional impulse response functions for rigid right circular tubes
• Estimation of Cerebral Blood Flow From Dynamic Susceptibility Contrast MRI Using A Tissue Model
• Automatic selection of arterial input function in DSC-MRI measurements for calculation of brain perfusion parameters using parametric modelling
• On cross-correlogram IRF’s estimators of two-output systems in spaces of continuous functions

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