Calcium buffers and L-type calcium channels as modulators of cardiac subcellular alternans

DOI10.1016/J.CNSNS.2020.105181MaRDI QIDQ2204483zbMATH OpenOpenAlexFDO

Authors Yi Ming Lai, Rüdiger Thul, S. Coombes

Publication date 15 October 2020

Published in Communications in Nonlinear Science and Numerical Simulation (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.cnsns.2020.105181

zbMATH Keywords

calcium cyclingluminal diffusionsaddle-node bifurcationsubcellular calcium alternanssynchrony

Mathematics Subject Classification ID

Cell biology (92C37) Biochemistry, molecular biology (92C40)

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Cites work

• A calcium-induced calcium release mechanism mediated by calsequestrin
• Complex patterns of subcellular cardiac alternans
• Feedback-control induced pattern formation in cardiac myocytes: a mathematical modeling study
• Models of calcium signalling
• Nagumo's equation
• Understanding cardiac alternans: A piecewise linear modeling framework

Cited in

(8)

• Role of CaMKII and PKA in early afterdepolarization of human ventricular myocardium cell: a computational model study
• In silico investigation into cellular mechanisms of cardiac alternans in myocardial ischemia
• Dynamics of adrenergic signaling in cardiac myocytes and implications for pharmacological treatment
• Linkages of calcium-induced calcium release in a cardiomyocyte simulated by a system of seven coupled partial differential equations
• Excitable dynamics in neural and cardiac systems
• Exploring impaired SERCA pump-caused alternation occurrence in ischemia
• Computational modelling of the initiation and development of spontaneous intracellular \(Ca^{2+}\) waves in ventricular myocytes
• Simulation of arrhythmogenic effect of rogue RyRs in failing heart by using a coupled model

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