Spatiotemporal regulation of GABA concentration in extracellular space by gliotransmission crucial for extrasynaptic receptor-mediated improvement of sensory tuning performance in schizophrenia

DOI10.1007/S10827-020-00755-4MaRDI QIDQ2210993zbMATH OpenOpenAlexWikidataFDO

Authors Osamu Hoshino, Rikiya Kameno, Jin Kubo, Kazuo Watanabe

Publication date 10 November 2020

Published in Journal of Computational Neuroscience (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s10827-020-00755-4

zbMATH Keywords

schizophreniaextracellular GABA concentrationflattened sensory tuningGABAergic gliotransmissionschizophrenic neural network model

Mathematics Subject Classification ID

Neural biology (92C20) Neural networks for/in biological studies, artificial life and related topics (92B20) Pathology, pathophysiology (92C32)

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Cites work

• Extracellular GABA assisting in organizing dynamic cell assemblies to shorten reaction time to sensory stimulation
• Improved perceptual learning by control of extracellular GABA concentration by astrocytic gap junctions
• Perceptual judgments via sensory-motor interaction assisted by cortical GABA

Cited in

(8)

• Extracellular GABA assisting in organizing dynamic cell assemblies to shorten reaction time to sensory stimulation
• Dopaminergic modulation of the P50 auditory-evoked potential in a computer model of the CA3 region of the hippocampus: its relationship to sensory gating in schizophrenia
• Inhibitory control of sensory gating in a computer model of the CA3 region of the hippocampus
• GABA diffusion across neuronal columns for efficient sensory tuning
• GABA Transporter Preserving Ongoing Spontaneous Neuronal Activity at Firing Subthreshold
• Effect of cortical extracellular GABA on motor response
• A model of neuregulin control of NMDA receptors on synaptic spines
• Regulation of ambient GABA levels by neuron-glia signaling for reliable perception of multisensory events

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