Optimal control analysis of a leukemia model under Imatinib treatment
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Publication:2228752
DOI10.1016/J.MATCOM.2015.03.002OpenAlexW632890797MaRDI QIDQ2228752FDOQ2228752
Authors: I. R. Rădulescu, D. Cândea, A. Halanay 
Publication date: 19 February 2021
Published in: Mathematics and Computers in Simulation (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.matcom.2015.03.002
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Functional-differential equations (including equations with delayed, advanced or state-dependent argument) (34Kxx) Physiological, cellular and medical topics (92Cxx)
Cites Work
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- Chemotherapy for tumors: An analysis of the dynamics and a study of quadratic and linear optimal controls
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- Optimal control of treatment in a mathematical model of chronic myelogenous leukemia
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- Drug resistance in cancer chemotherapy as an optimal control problem
- Optimal control applied to immunotherapy
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- Stability and Hopf bifurcation in a mathematical model of pluripotent stem cell dynamics
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- High frequency spikes in long period blood cell oscillations
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Cited In (24)
- Optimal impulsive intervention strategy for target mRNA knockout in RNAi process
- Progression, detection and remission: evolution of chronic myeloid leukemia using a three-stage probabilistic model
- Long-term treatment effects in chronic myeloid leukemia
- A control delay differential equations model of evolution of normal and leukemic cell populations under treatment
- A quantitative study on the role of TKI combined with Wnt/\(\beta\)-catenin signaling and IFN-\(\alpha\) in the treatment of CML through deterministic and stochastic approaches
- Optimal control for a delay differential system of Chronic Myelogenous Leukemia
- An analysis of strategic treatment interruptions during imatinib treatment of chronic myelogenous leukemia with imatinib-resistant mutations
- A mathematical model with time-varying delays in the combined treatment of chronic myeloid leukemia
- Optimal control applied to a generalized Michaelis-Menten model of CML therapy
- An optimal treatment strategy for a leukemia immune model governed by reaction-diffusion equations
- Optimization of cytostatic leukemia therapy in an advection-reaction-diffusion model
- Stability and controllability issues in mathematical modeling of the intensive treatment of leukemia
- Optimal control for resistance and suboptimal response in CML
- New Computational Tools for Modeling Chronic Myelogenous Leukemia
- Optimization for the intensive treatment of leukemia
- Optimal control in a mathematical model for leukemia therapy with phase constraints
- A mathematical model of Imatinib and interferon-Alpha combined treatment of chronic myeloid leukemia
- Optimization of combined leukemia therapy by finite-dimensional optimal control modeling
- Mathematical analysis and optimal control applied to the treatment of leukemia
- On optimal and suboptimal treatment strategies for a mathematical model of leukemia
- Mathematical analysis and global dynamics for a time-delayed chronic myeloid leukemia model with treatment
- Chemo and immunotherapy effects on stability regions of tumor models
- Global stability analysis and optimal control therapy of blood cell production process (hematopoiesis) in acute myeloid leukemia
- Optimal control of treatment in a mathematical model of chronic myelogenous leukemia
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