First passage time properties of miRNA-mediated protein translation

DOI10.1016/J.JTBI.2021.110863MaRDI QIDQ2235513zbMATH OpenOpenAlexFDO

Authors Kuheli Biswas, Mohit Kumar Jolly, Anandamohan Ghosh

Publication date 21 October 2021

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2021.110863

zbMATH Keywords

stochastic modellinggene regulationmiRNA

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

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(5)

• Dynamical features of the quasi-stationary microRNA-mediated protein translation process supported by eIF4F translation initiation factors
• Post-transcriptional regulation in the nucleus and cytoplasm: study of mean time to threshold (MTT) and narrow escape problem
• Modelling and analysis of miRNA regulation
• Dynamical analysis of the MicroRNA-mediated protein translation process
• Independent channels for miRNA biosynthesis ensure efficient static and dynamic control in the regulation of the early stages of myogenesis

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