Dynamics of kinesin motor proteins under longitudinal and sideways loads

DOI10.1016/J.JTBI.2021.110879MaRDI QIDQ2235535zbMATH OpenOpenAlexFDO

Authors Ping Xie

Publication date 21 October 2021

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2021.110879

zbMATH Keywords

dissociation ratemechanochemical coupling mechanismmolecular motorrun lengthsideways loadvelocity

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40)

Recommendations

• Mechanistic mathematical model of kinesin under time and space fluctuating loads
• Cooperativity of multiple kinesin-1 motors mechanically coupled through a shared load
• A Brownian dynamics model of kinesin in three dimensions incorporating the force-extension profile of the coiled-coil cargo tether
• Molecular mechanism of interaction between kinesin motors affecting their residence times on microtubule lattice and end
• Neck-linker tension and the locomotion of kinesin along microtubules

Cites work

• Non-tight and tight chemomechanical couplings of biomolecular motors under hindering loads

Cited in

(6)

• Force generation and step-size fluctuations in a dynein motor
• Measuring the limping of processive motor proteins
• Molecular mechanism of interaction between kinesin motors affecting their residence times on microtubule lattice and end
• Effect of small molecular crowders on dynamics of kinesin molecular motors
• Transport of track-interacted cargo by molecular motor
• A model of tubulin removal and exchange caused by kinesin motor walking on microtubule lattices

This page was built for publication: Dynamics of kinesin motor proteins under longitudinal and sideways loads

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2235535)