Evolution of mathematical models of cardiomyocyte electrophysiology

DOI10.1016/J.MBS.2021.108567MaRDI QIDQ2240263zbMATH OpenOpenAlexFDO

Authors Bogdan Amuzescu, Razvan Airini, Florin Bogdan Epureanu, Stefan A. Mann, Thomas Knott, Beatrice Mihaela Radu

Publication date 8 November 2021

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2021.108567

zbMATH Keywords

Markov modelsmathematical modelsHodgkin-Huxley modelscardiomyocytecardiac action potentialcardiomyocyte electrophysiology

Mathematics Subject Classification ID

Mathematical modeling or simulation for problems pertaining to biology (92-10) Physiology (general) (92C30) Research exposition (monographs, survey articles) pertaining to biology (92-02) Computational methods for problems pertaining to biology (92-08) Cell biology (92C37)

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Cites work

• scientific article; zbMATH DE number 637123 (Why is no real title available?)
• scientific article; zbMATH DE number 3806869 (Why is no real title available?)
• A Coupled System of PDEs and ODEs Arising in Electrocardiograms Modeling
• A two-current model for the dynamics of cardiac membrane
• Adams method for solving uncertain differential equations
• Automatic Computation of Nerve Excitation
• Automatic Computation of Nerve Excitation—Detailed Corrections and Additions
• MATCONT
• Mathematical model of the atrioventricular nodal double response tachycardia and double-fire pathology
• Mathematical models of the electrical action potential of Purkinje fibre cells
• Proceedings of the 9th International Conference on Computational Methods in Systems Biology
• Spontaneous onset of atrial fibrillation

Cited in

(9)

• A fast time integral finite difference method for a space-time fractional FitzHugh-Nagumo monodomain model in irregular domains
• scientific article; zbMATH DE number 1944198 (Why is no real title available?)
• A computational view of electrophysiological properties under different atrial fibrosis conditions
• Mathematical models of the electrical action potential of Purkinje fibre cells
• How drugs modulate the performance of the human heart
• Reducing complexity and unidentifiability when modelling human atrial cells
• Bifurcation analysis of a modified cardiac cell model
• Modelling and simulation for preclinical cardiac safety assessment of drugs with human iPSC-derived cardiomyocytes
• A discrete in continuous mathematical model of cardiac progenitor cells formation and growth as spheroid clusters (Cardiospheres)

Describes a project that uses

Uses Software

• CESE
• OpenCOR
• LabHEART
• MathML
• JSim
• CL_MATCONT
• CVODE
• AUTO
• MATCONT

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