A study case for the analysis of asymptotic expansions beyond the tQSSA for inhibitory mechanisms in enzyme kinetics.
From MaRDI portal
Publication:2274586
DOI10.1515/caim-2019-0019zbMath1422.34170OpenAlexW2968083217WikidataQ127388654 ScholiaQ127388654MaRDI QIDQ2274586
Alessandro Borri, Alberto Maria Bersani, Pierluigi Vellucci, A. Milanesi, Giovanna Tomassetti
Publication date: 1 October 2019
Published in: Communications in Applied and Industrial Mathematics (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1515/caim-2019-0019
Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Stability of solutions to ordinary differential equations (34D20) Singular perturbations of ordinary differential equations (34D15) Perturbations, asymptotics of solutions to ordinary differential equations (34E10)
Related Items
The total quasi-steady-state for multiple alternative substrate reactions ⋮ Uniform Asymptotic Expansions beyond the tQSSA for the Goldbeter--Koshland Switch ⋮ A study case for the analysis of asymptotic expansions beyond the tQSSA for inhibitory mechanisms in enzyme kinetics.
Cites Work
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Unnamed Item
- Quasi steady-state approximations in complex intracellular signal transduction networks - a word of caution
- A perturbation solution of Michaelis-Menten kinetics in a ``total framework
- Time-dependent closed form solutions for fully competitive enzyme reactions
- Deterministic and stochastic models of enzymatic networks-applications to pharmaceutical research
- The total quasi-steady-state approximation for complex enzyme reactions
- Krylov and steady-state techniques for the solution of the chemical master equation for the mitogen-activated protein kinase cascade
- Analysis of metabolic systems with complex slow and fast dynamics
- Applications of centre manifold theory
- Geometric singular perturbation theory for ordinary differential equations
- Normally hyperbolic invariant manifolds in dynamical systems
- Mathematical biology. Vol. 1: An introduction.
- Enzyme kinetics far from the standard quasi-steady-state and equilibrium approximations
- Antagonism and bistability in protein interaction networks
- Extending the quasi-steady state approximation by changing variables
- The total quasi-steady-state approximation is valid for reversible enzyme kinetics
- Quasi-steady-state kinetics at enzyme and substrate concentrations in excess of the Michaelis-Menten constant
- Reduced models of networks of coupled enzymatic reactions
- A study case for the analysis of asymptotic expansions beyond the tQSSA for inhibitory mechanisms in enzyme kinetics.
- Introducing total substrates simplifies theoretical analysis at non-negligible enzyme concentrations: pseudo first-order kinetics and the loss of zero-order ultrasensitivity
- Tihonov theory and center manifolds for inhibitory mechanisms in enzyme kinetics
- The total quasi-steady-state approximation for fully competitive enzyme reactions
- New trends and perspectives in nonlinear intracellular dynamics: one century from Michaelis-Menten paper
- The Quasi-Steady-State Assumption: A Case Study in Perturbation
- Introduction to Applied Nonlinear Dynamical Systems and Chaos
- Uniform Asymptotic Expansions beyond the tQSSA for the Goldbeter--Koshland Switch
- ASYMPTOTIC BEHAVIOUR OF SOLUTIONS TO CERTAIN PROBLEMS INVOLVING NON-LINEAR DIFFERENTIAL EQUATIONS CONTAINING A SMALL PARAMETER MULTIPLYING THE HIGHEST DERIVATIVES
- Singular Perturbations on the Infinite Interval