Analytical modeling and deep learning approaches to estimating RNA SHAPE reactivity from 3D structure

DOI10.4310/CIS.2019.V19.N3.A4MaRDI QIDQ2294411zbMATH OpenFDO

Authors Travis Hurst, Yuanzhe Zhou, Shijie Chen

Publication date 11 February 2020

Published in Communications in Information and Systems (Search for Journal in Brave)

Full work available at URL https://doi.org/10.4310/CIS.2019.V19.N3.A4

Mathematics Subject Classification ID

Artificial neural networks and deep learning (68T07) Biochemistry, molecular biology (92C40) Protein sequences, DNA sequences (92D20)

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• Applying a neural network to predict the thermodynamic parameters for an expanded nearest-neighbor model
• Building the library of RNA 3D nucleotide conformations using the clustering approach

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