Dynamic modeling of signal transduction by mTOR complexes in cancer

DOI10.1101/633891MaRDI QIDQ2328293zbMATH OpenOpenAlexWikidataFDO

Authors Mohammadreza Dorvash, Mohammad Farahmandnia, Pouria Mosaddeghi, Mitra Farahmandnejad, Hosein Saber, Mohammadhossein Khorraminejad-Shirazi, Amir Azadi, Iman Tavassoly

Publication date 10 October 2019

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1101/633891

zbMATH Keywords

cell signalingmathematical modelmTORrapamycinsystems biologysystems pharmacology

Mathematics Subject Classification ID

Cell biology (92C37) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

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(1)

• Computational modeling implicates protein scaffolding in p38 regulation of akt

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