The continuous morbidostat: a chemostat with controlled drug application to select for drug resistance mutants

DOI10.3934/CPAA.2020011MaRDI QIDQ2332301zbMATH OpenOpenAlexWikidataFDO

Authors Zhenzhen Chen, Sze-Bi Hsu, Ya-Tang Yang

Publication date 4 November 2019

Published in Communications on Pure and Applied Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3934/cpaa.2020011

zbMATH Keywords

mutationdrug resistancebacteriacontinuousmorbidostat

Mathematics Subject Classification ID

Medical applications (general) (92C50) Problems related to evolution (92D15) Growth and boundedness of solutions to ordinary differential equations (34C11)

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(2)

• The morbidostat: a bio-reactor that promotes selection for drug resistance in bacteria
• A spatio-temporal model of drug resistance in bacteria with mutations

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