Modeling the effect of mucin binding in the gut on drug delivery

DOI10.1007/S11538-018-0417-3MaRDI QIDQ2334388zbMATH OpenOpenAlexWikidataFDO

Authors Jeffrey Saltzman, Claus Bendtsen

Publication date 7 November 2019

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s11538-018-0417-3

zbMATH Keywords

ADMEintestinal mucus layermathematical modelprotein binding

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Finite difference methods for initial value and initial-boundary value problems involving PDEs (65M06) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Recommendations

• Drug absorption in the gastrointestinal tract: a mathematical model
• A mixture model for the dynamic of the gut mucus layer
• An analytical solution for the model of drug distribution and absorption in small intestine
• A mathematical model for drug delivery
• Enhanced electrodiffusive transport across a mucus layer

Cites work

• scientific article; zbMATH DE number 3109695 (Why is no real title available?)
• Partial differential equations. 3rd ed

Cited in

(5)

• What can mathematics do for drug development?
• Drug absorption in the gastrointestinal tract: a mathematical model
• An analytical solution for the model of drug distribution and absorption in small intestine
• A mixture model for the dynamic of the gut mucus layer
• Enhanced electrodiffusive transport across a mucus layer

Describes a project that uses

Uses Software

• Mathematica

This page was built for publication: Modeling the effect of mucin binding in the gut on drug delivery

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2334388)