Homogenization results for a coupled system of reaction-diffusion equations

DOI10.1016/J.NA.2019.06.004zbMATH Open1425.35096arXiv1906.05362OpenAlexW2951485487WikidataQ127664243 ScholiaQ127664243MaRDI QIDQ2338686FDOQ2338686

Authors: Carmen Perugia, Claudia Timofte, Giuseppe Cardone 

Publication date: 21 November 2019

Published in: Nonlinear Analysis. Theory, Methods \& Applications. Series A: Theory and Methods (Search for Journal in Brave)

Abstract: The macroscopic behavior of the solution of a coupled system of partial differential equations arising in the modeling of reaction-diffusion processes in periodic porous media is analyzed. Our mathematical model can be used for studying several metabolic processes taking place in living cells, in which biochemical species can diffuse in the cytosol and react both in the cytosol and also on the organellar membranes. The coupling of the concentrations of the biochemical species is realized via various properly scaled nonlinear reaction terms. These nonlinearities, which model, at the microscopic scale, various volume or surface reaction processes, give rise in the macroscopic model to different effects, such as the appearance of additional source or sink terms or of a non-standard diffusion matrix.

Full work available at URL: https://arxiv.org/abs/1906.05362

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zbMATH Keywords

homogenizationreaction-diffusion equationsnonlinear flux conditions

Mathematics Subject Classification ID

Biomechanical solid mechanics (74L15) PDEs in connection with fluid mechanics (35Q35) Homogenization in context of PDEs; PDEs in media with periodic structure (35B27) Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Fluid-solid interactions (including aero- and hydro-elasticity, porosity, etc.) (74F10) Flows in porous media; filtration; seepage (76S05) Physiological flows (76Z05) Reaction effects in flows (76V05)

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Cited In (13)

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• Mathematical analysis of a PDE-ODE coupled model of mitochondrial swelling with degenerate calcium ion diffusion
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• Derivation of an effective model for metabolic processes in living cells including substrate channeling
• Nonlinear coupled system in thin domains with corrugated boundaries for metabolic processes
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• Upscaling of a parabolic system with a large nonlinear surface reaction term
• Derivation of a Macroscopic Receptor-Based Model Using Homogenization Techniques
• An optimal control problem in a tubular thin domain with rough boundary
• Upscaling coupled heterogeneous diffusion reaction equations in porous media
• Homogenization of a nonlinear stochastic model with nonlinear random forces for chemical reactive flows in porous media
• Coupled reaction-diffusion systems and evolving microstructure: mathematical modelling and homogenization.
• Surface reactions on the cytoplasmatic membranes -- mathematical modeling of reaction and diffusion systems in a cell

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