Modeling the dynamics of hypoxia inducible factor-\(1\alpha\) (HIF-\(1\alpha\)) within single cells and 3D cell culture systems

DOI10.1016/j.mbs.2014.09.007zbMath1314.92056arXiv1409.4976OpenAlexW2017406281WikidataQ44913439 ScholiaQ44913439MaRDI QIDQ2343715

Joseph Leedale, R. N. Bearon, Anne Herrmann, Andreas Fercher, Violaine Sée, James Bagnall, Dmitri Papkovsky

Publication date: 6 May 2015

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1409.4976

zbMATH Keywords

spheroidshypoxiaHIF (hypoxia inducible factor)oxygen nanoprobesprolyl hydroxylase

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37)

Related Items (3)

Modeling hypoxia-related inflammation scenarios ⋮ Three-dimensional simulations of the cell growth and cytokinesis using the immersed boundary method ⋮ Modelling HIF-PHD dynamics and related downstream pathways

Cites Work

• Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway
• Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model
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