Computational characterization and design of SARS coronavirus receptor recognition and antibody neutralization

DOI10.1016/J.COMPBIOLCHEM.2007.02.005MaRDI QIDQ2373310zbMATH OpenOpenAlexDBLPWikidataFDO

Authors Yuan Zhang, Nan Zheng, Yang Zhong

Publication date 17 July 2007

Published in Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc7106420

zbMATH Keywords

Protein designSpike protein

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Biochemistry, molecular biology (92C40) Medical applications (general) (92C50)

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Cited in

(7)

• Electrostatic features for nucleocapsid proteins of SARS-CoV and SARS-CoV-2
• Computational modeling of protein conformational changes -- application to the opening SARS-CoV-2 spike
• Computational simulation of interactions between SARS coronavirus spike mutants and host species-specific receptors
• A molecular docking model of SARS-CoV S1 protein in complex with its receptor, human ACE2
• Structure of a Fab complex with the C-terminal fragment of merozoite surface protein-1 of Plasmodium vivax determined by computational docking
• Functional and structural characterization of Ebola virus glycoprotein (1976–2015) — Anin silicostudy
• Design of an engineered ACE2 as a novel therapeutics against COVID-19

Describes a project that uses

Uses Software

• FoldX
• SWISS-MODEL

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