Application of the convection-dispersion equation to modelling oral drug absorption

DOI10.1007/s11538-006-9122-8zbMath1133.92327WikidataQ42145370 ScholiaQ42145370MaRDI QIDQ2426243

Jan I. Freijer, Teun M. Post, Bart A. Ploeger, Joost Dejongh, Meindert Danhof

Publication date: 22 April 2008

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-006-9122-8

zbMATH Keywords

inverse Gaussian distribution; pharmacokinetics; gastric emptying; NONMEM; paracetamol

Mathematics Subject Classification ID

35Q92: PDEs in connection with biology, chemistry and other natural sciences

92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)

92C50: Medical applications (general)

65M99: Numerical methods for partial differential equations, initial value and time-dependent initial-boundary value problems

Uses Software

• NONMEM

Cites Work

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• On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed