A Bayesian approach for investigating the risk of QT prolongation

DOI10.1080/15598608.2009.10411936MaRDI QIDQ2431690zbMATH OpenOpenAlexWikidataFDO

Authors Suraj P. Anand, Sujit K. Ghosh

Publication date 18 April 2011

Published in Journal of Statistical Theory and Practice (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc3157648

zbMATH Keywords

Bayesian inferenceMonte Carlo simulationICH E14QT/QTc intervalthorough QT/QTc study

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05)

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• Bioequivalence and statistics in clinical pharmacology.

Cited in

(1)

• Machine learning in drug development: characterizing the effect of 30 drugs on the QT interval using Gaussian process regression, sensitivity analysis, and uncertainty quantification

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