Bayesian object classification of gold nanoparticles

DOI10.1214/12-AOAS616MaRDI QIDQ2443129zbMATH OpenOpenAlexFDO

Authors Bledar A. Konomi, Soma S. Dhavala, Jianhua Z. Huang, Subrata Kundu, David Huitink, Hong Liang, Yu Ding, Bani Mallick

Publication date 4 April 2014

Published in The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1312.1560, https://projecteuclid.org/euclid.aoas/1372338462

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to physics (62P35)

Abstract: The properties of materials synthesized with nanoparticles (NPs) are highly correlated to the sizes and shapes of the nanoparticles. The transmission electron microscopy (TEM) imaging technique can be used to measure the morphological characteristics of NPs, which can be simple circles or more complex irregular polygons with varying degrees of scales and sizes. A major difficulty in analyzing the TEM images is the overlapping of objects, having different morphological properties with no specific information about the number of objects present. Furthermore, the objects lying along the boundary render automated image analysis much more difficult. To overcome these challenges, we propose a Bayesian method based on the marked-point process representation of the objects. We derive models, both for the marks which parameterize the morphological aspects and the points which determine the location of the objects. The proposed model is an automatic image segmentation and classification procedure, which simultaneously detects the boundaries and classifies the NPs into one of the predetermined shape families. We execute the inference by sampling the posterior distribution using Markov chain Monte Carlo (MCMC) since the posterior is doubly intractable. We apply our novel method to several TEM imaging samples of gold NPs, producing the needed statistical characterization of their morphology.

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Cited in

(2)

• Fast dynamic nonparametric distribution tracking in electron microscopic data
• Bayesian object classification of gold nanoparticles

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