Invariance principle for the coverage rate of genomic physical mappings

DOI10.1214/105051605000000584zbMATH Open1108.60044arXivmath/0510036OpenAlexW2034339129MaRDI QIDQ2496501FDOQ2496501

Authors: Didier Piau 

Publication date: 10 July 2006

Published in: The Annals of Applied Probability (Search for Journal in Brave)

Abstract: We study some stochastic models of physical mapping of genomic sequences. Our starting point is a global construction of the process of the clones and of the process of the anchors which are used to map the sequence. This yields explicit formulas for the moments of the proportion occupied by the anchored clones, even in inhomogeneous models. This also allows to compare, in this respect, inhomogeneous models to homogeneous ones. Finally, for homogeneous models, we provide nonasymptotic bounds of the variance and we prove functional invariance results.

Full work available at URL: https://arxiv.org/abs/math/0510036

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zbMATH Keywords

coverage processesinhomogeneous Poisson processesgenomic sequencesanchored islands

Mathematics Subject Classification ID

Point processes (e.g., Poisson, Cox, Hawkes processes) (60G55) Protein sequences, DNA sequences (92D20) Functional limit theorems; invariance principles (60F17)

Cites Work

• The functional central limit theorem for strongly mixing processes
• Percolation of Poisson sticks on the plane

Cited In (4)

• Genome mapping by random anchoring: A discrete theoretical analysis
• Title not available (Why is that?)
• Genome mapping by nonrandom anchoring: a discrete theoretical analysis.
• Island length distribution in genome sequencing.

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